Trimix Injections (Intracavernosal)

How Trimix Works: Effective ED Treatment Through Penile Injections
What it is
A compounded mixture (typically alprostadil, papaverine, phentolamine) injected into the lateral penile shaft using a small insulin-type needle.
Who it’s for
Moderate to severe ED or when pills are ineffective or contraindicated.
How it works
Smooth-muscle relaxation increases arterial inflow. Erection occurs in 5–15 minutes.
What to expect
- In-clinic teaching session
- First-dose titration
- Most men self-inject confidently after 1–2 supervised tries.
Risks/considerations
- Bruising, ache, rare priapism
- We provide clear instructions and de-escalation meds if needed.
Follow-up
- Dose refinement over the first 2–3 uses
- Periodic check-ins every 3–6 months.
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What our patients says

Dr. Martinez and Dr. Williams are both exceptional. Their expertise and care truly make a difference!

Dr Martinez and Dr Williams are AMAZING! I highly recommend for all men to get checked out! Dont wait the sooner the better !

I've been coming here for about 4 or 5 years now and the customer service is great. They're good for the guys out there, but by far I want to say that Danielle needs to stand out and be rewarded I heard professionalism, heard energy on the phone and just very friendly and makes you feel at home.
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Frequently Asked Questions
What can I do to get started?
Take the Men’s Health Quiz found on this website. If the questions you answered affect your health in any way, call us at The Y Factor or make an appointment online and our specialists will evaluate your urological health and start a specialized treatment plan specifically for you.
Why does The Y Factor specialize in men’s health?
The Y Factor was named for the Y-chromosome, the factor that determines male characteristics. Our facilities were created by men, for men, with the expertise of male urological health. Our team believes in finding the underlying source of men’s health problems so they can customize a specific treatment plan to improve current health issues along with one’s overall quality of life.
Are the treatments/surgeries at The Y Factor painful?
We take all precautions to ensure you are in as little pain as possible. Many of our patients have reported low pain levels, around 1-2 on a scale of 10.
Yes, we accept all major insurance plans:
At The Y Factor, we realize that medical care can be expensive. In an attempt to help you – our patients,
we can also work with the “Out of Network” benefits of most health insurance plans, and we accept Care Credit.