A varicocele is one of the most common and well-established causes of male infertility, yet it is also one of the most frequently underdiagnosed. A varicocele refers to abnormal dilation of the veins within the scrotum that drain blood away from the testes. These veins play a critical role in regulating testicular temperature and blood flow—two factors essential for normal sperm production.

At The Y Factor, varicoceles are evaluated as part of a diagnostic-first male fertility assessment, recognizing that their impact extends beyond sperm count alone and may influence motility, morphology, DNA integrity, and pregnancy outcomes.

Medical illustration of a sperm cell penetrating an egg cell during the fertilization process.
Hand holding a medical model of the male reproductive system showing internal pelvic anatomy.

What Is a Varicocele?

A varicocele develops when the valves within the scrotal veins fail to function properly, allowing blood to pool around the testes. This venous congestion disrupts the delicate testicular environment required for healthy sperm production.

Varicoceles most commonly occur on the left side due to differences in venous anatomy, though bilateral varicoceles are not uncommon. Severity ranges from small, subclinical varicoceles detectable only by ultrasound to larger varicoceles that can be felt on physical examination.

How Varicoceles Affect Male Fertility

Varicoceles impair fertility through multiple mechanisms that act together over time.

This is the default text value

Testicular Temperature Regulation

The testes are positioned outside the body to maintain a temperature slightly cooler than core body temperature. Varicoceles interfere with this cooling mechanism, leading to elevated testicular temperature. Even modest temperature increases can disrupt sperm production and maturation.

This is the default text value

Blood Flow, Oxygenation, and Oxidative Stress

Abnormal venous drainage reduces oxygen delivery and increases oxidative stress within the testes. Oxidative stress damages sperm-producing cells and sperm membranes, impairing function and genetic integrity.

Medical professional pointing to a cross-section model of the male pelvic anatomy.

How Common Are Varicoceles in Men With Infertility?

Varicoceles are found in a substantial proportion of men evaluated for infertility and are even more common among men with secondary infertility (difficulty conceiving after previously fathering a child). This prevalence highlights the importance of actively evaluating for varicoceles during male fertility assessment.

Male patient sitting on an examination table during a medical consultation with a healthcare provider.

Signs and Symptoms of Varicocele-Related Fertility Issues

Many men with varicoceles have no symptoms. When present, symptoms may include:

  • dull scrotal aching or heaviness
  • discomfort that worsens with standing or activity
  • visible or palpable scrotal veins

In many cases, infertility or abnormal semen analysis is the first indication that a varicocele is clinically relevant.

How Varicoceles Affect Sperm Quality

Evaluation typically begins with a semen analysis to assess sperm count, motility, and morphology, which helps determine whether a varicocele is affecting sperm production or function.

This is the default text value

Sperm Count

Varicoceles are associated with reduced sperm production due to chronic testicular stress and impaired spermatogenesis.

This is the default text value

Sperm Motility

Motility may be reduced as oxidative stress interferes with sperm energy production and maturation.

This is the default text value

Sperm Morphology and DNA Integrity

Varicoceles are strongly associated with abnormal sperm morphology and increased sperm DNA fragmentation. These defects may impair fertilization and increase miscarriage risk even when conception occurs.

Medical professional holding a clipboard while consulting with a male patient in a clinical exam room.

Why Varicoceles Are Often Missed in Fertility Evaluation

Varicoceles are frequently overlooked because:

  • many men are asymptomatic
  • physical exam findings can be subtle
  • imaging is not routinely performed
  • male evaluation is often delayed

Without targeted evaluation, varicoceles may remain undiagnosed despite their clinical significance.

How Varicocele-Related Fertility Issues Are Evaluated

Physical Examination

A focused examination by an experienced clinician may identify varicoceles, particularly under specific conditions.

Scrotal Ultrasound

Ultrasound confirms the diagnosis, assesses severity, evaluates testicular size, and identifies bilateral disease.

Semen Analysis and Hormonal Testing

Semen analysis reveals functional impact, while hormonal testing assesses testicular reserve and endocrine contribution.

This is the default text value

Varicoceles and Pregnancy Outcomes

Varicoceles have been associated with:

  • reduced natural conception rates
  • prolonged time to pregnancy
  • poorer assisted reproduction outcomes
  • increased miscarriage risk in some cases

Understanding their role helps guide informed fertility planning.

This is the default text value

Management Depends on the Individual Clinical Context

Not all varicoceles require intervention. Management depends on fertility goals, semen abnormalities, symptoms, and partner factors. Diagnostic clarity determines whether observation, optimization, or referral is appropriate.

This is the default text value

When to Seek Evaluation for Varicocele and Fertility

Evaluation should be considered when:

  • semen abnormalities are present
  • infertility is unexplained
  • scrotal discomfort exists
  • future fertility is a concern

Schedule a Male Fertility Evaluation

The Y Factor provides comprehensive male fertility evaluation in Houston, focused on identifying varicocele-related contributors and guiding evidence-based care.